Mass Spectrometry

Innovating mass spectrometry sample prep through automation

Proteomics research presents issues of limited and variable sample material and degradation, vast dynamic range and a plethora of post-translational modifications. Whether analyzing a single protein or an entire proteome, automating the sample prep for mass spectrometry analysis can help achieve enhanced reproducibility while also delivering cost- and time-saving benefits.

The Biomek liquid handling systems present a dynamic range of pipetting capabilities that can be configured for semi- or complete automation for your sample prep for mass spectrometry analysis.

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Automated Sample Preparation for Analysis of 25-OH Vitamin D3 and 25-OH-Vitamin D2 by LC/MS/MS In this work, we demonstrate the feasibility of automating the sample preparation for liquid chromatography-tandem mass spectrometry (LC/MS/MS) analysis of 25-OH-Vitamin D2 and 25-OH-Vitamin D3.
Automated Sample Preparation for the Monitoring of Ethanol Metabolites in Urine by LC-MS/MS In this application note, we describe an LC-MS/MS method for the analysis of EtG and EtS in urine employing a simple, automated sample preparation methodology using a liquid handling-based automation system.
Innovations that Reshape Sample Prep for Bioanalysis Proteomics research presents issues of limited and variable sample material and degradation, vast dynamic range and a plethora of post-translational modifications

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