RNA Extraction from FFPE Tissue

FormaPure XL RNA

With our SPRI paramagnetic bead-based chemistry, you can extract RNA from even the most challenging formalin-fixed paraffin-embedded (FFPE) tissue samples.

For optimum convenience, you receive knowledgeable support for reagents and automation methods from a single vendor.

  • Fragment analysis shows FormaPure XL RNA kits isolate RNA with the best possible integrity—even from 10+-year-old tissue blocks
  • Performance demonstrated with a variety of sample and tissue types
  • Scalable based on throughput
  • Demonstrated performance with 7x 10 μM curls

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Explore From FFPE Tissue Models

FormaPure XL RNA Visual Workflow

Genomics FormaPure XL RNA Workflow

Product Specifications: FormaPure XL RNA

Application Uses RNA Isolation, RNA Extraction, RNA Sequencing, Nucleic Acid Sample Prep
Format Liquid
Starting Sample Material FFPE (formalin fixed paraffin embedded) tissue.
Automated Available Yes
Item Specifications Referenced C36000

Content and Resources

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Using FormaPure XL RNA Reagent to Put the Brakes on Prostate Cancer (PDF) Using cancer-specific molecular biomarkers, Dr. Palanisamy’s lab is currently working to understand the genetic complexity of multifocal prostate cancer and its intra- and inter-tumor heterogeneity
Automated Demonstrated Methods for Biomek i-Series Workstations (PDF) Learn more about automated NGS Library Construction and Nucleic Acid Sample Preparation methods for Biomek i-Series workstations
Flyer: Genomic Solutions Collaboration Program (PDF) Through this program, you’ll have exclusive access to Beckman Coulter Life Sciences genomic technologies, data analysis tools and application scientists.
Transcriptomic analysis reveals differential gene expression in African American prostate cancer samples (PDF) In this application note, we conducted a proof of principle study to identify transcriptomic signatures in the AA population using in-house PCa AA FFPE and fresh frozen samples.
Manual or Automated RNA, DNA or Total Nucleic Acid Extraction from FFPE Tissues FormaPure XL reagent kits represent a single-chemistry system with demonstrated capability for use in Next-Generation Sequencing (NGS) as well as other downstream applications including qPCR. Maximizing integrity, yield and purity from an FFPE sample is required to minimize the risk of losing important genetic information

Technical Documents

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