Kappa Chain Antibodies

Kappa (κ) chain is a 25 kDa polypeptide that results from papain cleavage of the IgG molecule, encoded by the human immunoglobulin kappa locus (IGK) on chromosome 2. The subunit structure of IgG comprises 2 light chains and 2 heavy chains. Each light chain is composed of two tandem immunoglobulin domains: a) one variable domain (VL) and b) one constant (CL) domain. While the VL show considerable sequence diversity the CL shows internal homology with repeating units. Anti-Kappa antibodies recognize the Kappa light chain of immunoglobulins expressed at the surface of a cellular subpopulation corresponding to approximately 2/3 of mature B lymphocytes in peripheral blood. This light chain is also found on the surface of a sub‑population of immature bone marrow B lymphocytes.


Clone: Polyclonal Isotype: F(ab’)2 Goat

Clone: Polyclonal Isotype: F(ab’)2 Rabbit

Explore Kappa Chain Antibodies

Content and Resources

Building IVDR compliant panels for haematological disorders wallchart Diagnostic purpose of the IVDR conjugated antibodies
Building IVDR compliant panels for haematological disorders wallchart Diagnostic purpose of the IVDR conjugated antibodies
7 Tips for Multi Color Panel Design Seven Tips for Achieving the Perfect Panel for Multicolor Flow Cytometry
SuperNova v428: New Bright Polymer Dye for Flow Cytometry Applications In this paper you will discover the latest generation of polymer dyes for flow cytometry applications – SuperNova fluorochromes.