Microbioreactor Publications
| Year | Title | Journal | Authors | Link |
|---|---|---|---|---|
| 2022 | Developing a fluorometric urease activity microplate assay suitable for automated microbioreactor experimentsr | Frontiers | Frédéric Lapierre, Isabel Bolz, Jochen Büchs, Robert Huber |
https://www.frontiersin.org/articles/10.3389/fbioe.2022.936759/full |
| 2022 | Isolation and structural characterization of exopolysaccharide from marine Bacillus sp. and its optimization by Microbioreactor | Science Direct | Vasudev S. Wagh, Madhukar S.Said, Jagadish S. Bennale, Syed G.Dastager | |
| 2022 | Therapeutic enzyme engineering using a generative neural network | Scientific Reports | Andrew Giessel, Athanasios Dousis, Kanchana Ravichandran, Kevin Smith, Sreyoshi Sur, Iain McFadyen, Wei Zheng & Stuart Licht | https://doi.org/10.1038/s41598-022-05195-x |
| 2021 | Microbioreactor-assisted cultivation workflows for time-efficient phenotyping of protein producing Aspergillus niger in batch and fed-batch mode | Biotechnoly Progress | Roman Jansen, Holger Morschett, Dennis Hasenklever, Matthias Moch, Wolfgang Wiechert, Marco Oldiges | https://doi.org/10.1002/btpr.3144 |
| 2021 | A fully automated pipeline for the dynamic at‐line morphology analysis of microscale Aspergillus cultivation | Fungal Biol Biotechnol | Roman Jansen, Kira Küsters, Holger Morschett, Wolfgang Wiechert and Marco Oldiges | https://doi.org/10.1186/s40694-021-00109-4 |
| 2021 | High‑throughput microbioreactor provides a capable tool for early stage bioprocess development | Scientific Reports | Mathias Fink, Monika Cserjan‑Puschmann, Daniela Reinisch and Gerald Striedner | https://doi.org/10.1038/s41598-021-81633-6 |
| 2021 | Butanol production from lignocellulosic sugars by Clostridium beijerinckii in microbioreactors | Biotechnology for Biofuels | Cansu Birgen, Kristin F. Degnes, Sidsel Markussen, Alexander Wentzel and Håvard Sletta | https://doi.org/10.1186/s13068-021-01886-1 |
| 2020 | Revealing nutritional requirements of MICP‑relevant Sporosarcina pasteurii DSM33 for growth improvement in chemically defined and complex media | Scientific Reports | Frédéric M. Lapierre, Jakob Schmid, Benjamin Ederer, Nina Ihling, Jochen Büchs & Robert Huber | https://doi.org/10.1038/s41598-020-79904-9 |
| 2020 | Machine learning for metabolic engineering: A review | Metabolic Engineering | Christopher E. Lawson, Jose Manuel Martí, Tijana Radivojevic, Sai Vamshi R. Jonnalagadda, Reinhard Gentz, Nathan J. Hillson, Sean Peisert, Joonhoon Kim, Blake A. Simmons, Christopher J. Petzold, Steven W. Singer, Aindrila Mukhopadhyay, Deepti Tanjore, Joshua G. Dunn, Hector Garcia Martin | https://doi.org/10.1016/j.ymben.2020.10.005 |
| 2020 | The GATA Transcription Factor Gaf1 Represses tRNAs, Inhibits Growth, and Extends Chronological Lifespan Downstream of Fission Yeast TORC1 | Cell Reports | María Rodríguez-López, Suam Gonzalez, Olivia Hillson, Victor A. Tallada, Jürg Bähler, Charalampos Rallis | https://doi.org/10.1016/j.celrep.2020.02.058 |
| 2020 | Small scale screening of yeast strains enables high-throughput evaluation of performance in lignocellulose hydrolysates | Bioresource Technology Reports | Marlous van Dijk, Ignis Trollmann, Margarete Alice Fontes Saraiva, Rogelio Lopes Brandão, Lisbeth Olsson, Yvonne Nygård | https://doi.org/10.1016/j.biteb.2020.100532 |
| 2020 | Adaptive laboratory evolution of Pseudomonas putida KT2440 improves p-coumaric and ferulic acid catabolism and tolerance | Metabolic Engineering Communications | Elsayed T. Mohamed, Allison Z. Werner, Davinia Salvachúa, Christine A. Singer, Kiki Szostkiewicz, Manuel Rafael Jiménez-Díaz, Thomas Eng, Mohammad S. Radi, Blake A. Simmons, Aindrila Mukhopadhyay, Markus J. Herrgård, Steven W. Singer,Gregg T. Beckham, Adam M. Feist | https://doi.org/10.1016/j.mec.2020.e00143 |
| 2020 | Formulating bacterial endophyte: Pre-conditioning of cells and the encapsulation in amidated pectin beads | Biotechnology Reports | Mauricio Cruz Barrera, Desiree Jakobs-Schoenwandt, Martha Isabel Gómez, Juan Serrato, Silke Ruppel, Anant V. Patel | https://doi.org/10.1016/j.btre.2020.e00463 |
| 2020 | Genome Sequence and Characterization of Five Bacteriophages Infecting Streptomyces coelicolor and Streptomyces venezuelae: Alderaan, Coruscant, Dagobah, Endor1 and Endor2 | Viruses | Aël Hardy, Vikas Sharma, Larissa Kever and Julia Frunzke | https://doi.org/10.3390/v12101065 |
| 2020 | A unified design allows fine-tuning of biosensor parameters and application across bacterial species | Metabolic Engineering Communications | Christiane Katharina Sonntag, Lion Konstantin Flachbart, Celine Maass, Michael Vogt, Jan Marienhagen | https://doi.org/10.1016/j.mec.2020.e00150 |
| 2020 | Multidimensional engineering of Saccharomyces cerevisiae for efficient synthesis of medium-chain fatty acids | Nature Catalysis | Zhiwei Zhu, Yating Hu, Paulo Gonçalves Teixeira, Rui Pereira, Yun Chen, Verena Siewers and Jens Nielsen | https://doi.org/10.1038/s41929-019-0409-1 |
| 2019 | Development of a novel, robust and cost-efficient process for valorizing dairy waste exemplified by ethanol production | Microb Cell Fact. | Jing Shen, Jun Chen, Peter Ruhdal Jensen and Christian Solem | https://doi.org/10.1186/s12934-019-1091-3 |
| 2019 | Butanol production from lignocellulosic biomass: revisiting fermentation performance indicators with exploratory data analysis | Biotechnol Biofuels | Cansu Birgen, Peter Dürre, Heinz A. Preisig and Alexander Wentzel | https://doi.org/10.1186/s13068-019-1508-6 |
| 2019 | Less Sacrifice, More Insight: Repeated Low-Volume Sampling of Microbioreactor Cultivations Enables Accelerated Deep Phenotyping of Microbial Strain Libraries | Biotechnol J. | Johannes Hemmerich, Niklas Tenhaef, Carmen Steffens, Jannick Kappelmann, Marc Weiske, Sebastian J Reich, Wolfgang Wiechert, Marco Oldiges, Stephan Noack | https://doi.org/10.1002/biot.201800428 |
| 2019 | Glucose-containing polymer rings enable fed-batch operation in microtiter plates with parallel online measurement of scattered light, fluorescence, dissolved oxygen tension, and pH | Biotechnol Bioeng. | Tobias Habicher, Vroni Czotscher, Tobias Klein, Andreas Daub, Timm Keil, Jochen Büchs | https://doi.org/10.1002/bit.27077 |
| 2019 | A FRET-based biosensor for the quantification of glucose in culture supernatants of mL scale microbial cultivations | Microb Cell Fact. | Julia Otten, Niklas Tenhaef, Roman P Jansen, Johannes Döbber, Lisa Jungbluth, Stephan Noack, Marco Oldiges, Wolfgang Wiechert, Martina Pohl | https://doi.org/10.1186/s12934-019-1193-y |
| 2019 | Function of L-Pipecolic Acid as Compatible Solute in Corynebacterium glutamicum as Basis for Its Production Under Hyperosmolar Conditions | Front Microbiol. | Fernando Pérez-García, Luciana F. Brito, and Volker F. Wendisch | https://doi.org/10.3389/fmicb.2019.00340 |
| 2019 | The two model organisms E. coli and H. polymorpha were cultivated in the fed-batch microtiter plate to investigate the general applicability for microbial systems. | J Biol Eng. | T. Keil, B. Dittrich, C. Lattermann, T. Habicher, and J. Büchs | https://doi.org/10.1186/s13036-019-0147-6 |
| 2019 | Alone at last! - Heterologous expression of a single gene is sufficient for establishing the five-step Weimberg pathway in Corynebacterium glutamicum | Metab Eng Commun. | Christian Brüsseler, Anja Späth, Sascha Sokolowsky, and Jan Marienhagen | https://doi.org/10.1016/j.mec.2019.e00090 |
| 2019 | Parallelized microscale fed-batch cultivation in online-monitored microtiter plates: implications of media composition and feed strategies for process design and performance | Journal of Industrial Microbiology & Biotechnology | Holger Morschett, Roman Jansen, Christian Neuendorf, Matthias Moch, Wolfgang Wiechert, Marco Oldiges | https://doi.org/10.1007/s10295-019-02243-w |
| 2019 | A closer look at Aspergillus: online monitoring via scattered light enables reproducible phenotyping | Fungal Biology and Biotechnology | Roman P. Jansen, Carina Beuck, Matthias Moch, Bianca Klein, Kira Küsters, Holger Morschett, Wolfgang Wiechert and Marco Oldiges | https://doi.org/10.1186/s40694-019-0073-x |
| 2019 | Innovative microscale workflow from fungi cultures to Cell Wall-Degrading Enzyme screening | Microbial Biotechnology, | Roxane Raulo, Egon Heuson, Ali Siah, Vincent Phalip and Renato Froidevaux | https://doi.org/10.1111/1751-7915.13405 |
| 2019 | Engineering Robust Production Microbes for Large-Scale Cultivation | Trends in Microbiology | Maren Wehrs, Deepti Tanjore, Thomas Eng, Jeff Lievense, Todd R. Pray, and Aindrila Mukhopadhyay | https://doi.org/10.1016/j.tim.2019.01.006 |
| 2019 | Engineered microbial biofuel production and recovery under supercritical carbon dioxide | Nature Communications | J. T. Boock, A. J. E. Freedman, G. A. Tompsett, S. K. Muse, A. J. Allen, L. A. Jackson, B. Castro-Dominguez, M. T. Timko, K. L. J. Prather & J. R. Thompson | https://doi.org/10.1038/s41467-019-08486-6 |
| 2018 | Metabolic engineering of Corynebacterium glutamicum for the production of cis, cis-muconic acid from lignin | Microb Cell Fact. | Judith Becker, Martin Kuhl, Michael Kohlstedt, Sören Starck, and Christoph Wittmann | https://doi.org/10.1186/s12934-018-0963-2 |
| 2018 | Fermentative Production of N-Methylglutamate From Glycerol by Recombinant Pseudomonas putida | Front Bioeng Biotechnol. | Melanie Mindt, Tatjana Walter, Joe Max Risse, and Volker F. Wendisch | https://doi.org/10.3389/fbioe.2018.00159 |
| 2018 | Germination and Growth Analysis of Streptomyces lividans at the Single-Cell Level Under Varying Medium Compositions | Front Microbiol. | Joachim Koepff, Christian Carsten Sachs, Wolfgang Wiechert, Dietrich Kohlheyer, Katharina Nöh, Marco Oldiges, and Alexander Grünberger | https://doi.org/10.3389/fmicb.2018.02680 |
| 2018 | One-step process for production of N-methylated amino acids from sugars and methylamine using recombinant Corynebacterium glutamicum as biocatalyst | Sci Rep. | Melanie Mindt, Joe Max Risse, Hendrik Gruß, Norbert Sewald, Bernhard J. Eikmanns, and Volker F. Wendisch | https://doi.org/10.1186/s12934-018-0968-x |
| 2018 | Production of Food and Feed Additives From Non-food-competing Feedstocks: Valorizing N-acetylmuramic Acid for Amino Acid and Carotenoid Fermentation With Corynebacterium glutamicum | Front Microbiol. | Elvira Sgobba, Luisa Blöbaum, and Volker F. Wendisch | https://doi.org/10.3389/fmicb.2018.02046 |
| 2018 | High‑throughput optimization of medium components and culture conditions for the efficient production of a lipopeptide pseudofactin by Pseudomonas fluorescens BD5 | Biniarz et al. Microb Cell Fact | Piotr Biniarz, François Coutte, Frédérique Gancel and Marcin Łukaszewicz | https://doi.org/10.1186/s12934-018-0968-x |
| 2018 | A bio-based route to the carbon-5 chemical glutaric acid and to bionylon-6,5 using metabolically engineered Corynebacterium glutamicum | Green Chem. | Christina Maria Rohles, Lars Gläser, Michael Kohlstedt, Gideon Gießelmann, Samuel Pearson, Aránzazu del Campo, Judith Beckera and Christoph Wittmann | https://doi.org/10.1039/C8GC01901K |
| 2018 | Microbioreactor Systems for Accelerated Bioprocess Development | Biotechnol. J. | Johannes Hemmerich, Stephan Noack, Wolfgang Wiechert, and Marco Oldiges | https://doi.org/10.1002/biot.201700141 |
| 2018 | Glucose-Dependent Promoters for Dynamic Regulation of Metabolic Pathways | Frontiers in Bioengineering and Biotechnology, | Maury Jérôme, Kannan Soumya, Jensen Niels B., Öberg Fredrik K., Kildegaard Kanchana R., Forster Jochen, Nielsen Jens, Workman Christopher T., Borodina Irina | https://doi.org/10.3389/fbioe.2018.00063 |
| 2018 | A bio-based route to the carbon-5 chemical glutaric acid and to bionylon-6,5 using metabolically engineered Corynebacterium glutamicum | Green Chem. | Christina Maria Rohles, Lars Gläser, Michael Kohlstedt, Gideon Gießelmann, Samuel Pearson, Aránzazu del Campo, Judith Beckera and Christoph Wittmann | https://doi.org/10.1039/C8GC01901K |
| 2018 | An optogenetic toolbox of LOV-based photosensitizers for light-driven killing of bacteria | Scientific Reports | S. Endres, M. Wingen, J. Torra, R. Ruiz-González, T. Polen, G. Bosio, N. L. Bitzenhofer, F. Hilgers, T. Gensch, S. Nonell, K.-E. Jaeger and T. Drepper | https://doi.org/10.1038/s41598-018-33291-4 |
| 2018 | Layered dynamic regulation for improving metabolic pathway productivity in Escherichia coli | Proceedings of the National Academy of Sciences | Stephanie J. Doong, Apoorv Gupta and Kristala L. J. Prather | https://doi.org/10.1073/pnas.1716920115 |
| 2018 | Doing More With Less: Using High-Throughput and Parallel Experimental Systems to Enhance Learning | IATED Digital Library | V. Xiao, J. Abdul-Raheem, J.F. Hamel | https://library.iated.org/view/XIAO2018DOI |
| 2017 | On the catabolism of amino acids in the yeast Dekkera bruxellensis and the implications for industrial fermentation processes | Wiley Online Library | Denise Castro Parente, Danielli Batista Bezerra Cajueiro, Irina Charlot Peña Moreno, Fernanda Cristina Bezerra Leite, Will De Barros Pita, Marcos Antonio De Morais Jr | https://doi.org/10.1002/yea.3290 |
| 2017 | Managing the SOS Response for Enhanced CRISPR-Cas-Based Recombineering in E. coli through Transient Inhibition of Host RecA Activity | ACS Synth. Biol. | Eirik Adim Moreb, Benjamin Hoover, Adam Yaseen, Nisakorn Valyasevi, Zoe Roecker, Romel Menacho-Melgar, and Michael D. Lynch | https://doi.org/10.1021/acssynbio.7b00174 |
| 2017 | The Experiment Data Depot: A Web-Based Software Tool for Biological Experimental Data Storage, Sharing, and Visualization | ACS Synth. Biol. | William C. Morrell, Garrett W. Birkel, Mark Forrer, Teresa Lopez, Tyler W. H. Backman, Michael Dussault, Christopher J. Petzold et al. | https://doi.org/10.1021/acssynbio.7b00204 |
| 2017 | Identification of genes affecting alginate biosynthesis in Pseudomonas fluorescens by screening a transposon insertion library | BMC genomics | Ertesvåg, H., Sletta, H., Senneset, M., Sun, Y. Q., Klinkenberg, G., Konradsen, T. A., Ellingsen, T. E., and Valla, S. | https://doi.org/10.1186/s12864-016-3467-7 |
| 2017 | CRISPR/Cas9-based genome editing for simultaneous interference with gene expression and protein stability | Nucleic Acids Research | Virginia Martinez, Ida Lauritsen, Tonja Hobel, Songyuan Li, Alex Toftgaard Nielsen and Morten H. H. Nørholm | https://doi.org/10.1093/nar/gkx797 |
| 2017 | Fast and reliable strain characterization of Streptomyces lividans through micro-scale cultivation | Biotechnol Bioeng. | Koepff J., Keller M., Tsolis K.C., Busche T., Rückert C., Hamed M.B., Anné J., Kalinowski J., Wiechert W., Economou A., Oldiges M. | https://doi.org/10.1002/bit.26321 |
| 2017 | Prediction of Escherichia coli expression performance in microtiter plates by analyzing only the temporal development of scattered light during culture | Journal of Biological Engineering | Ladner T., Mühlmann M., Schulte A., Wandrey G. and Büchs J. | https://doi.org/10.1186/s13036-017-0064-5 |
| 2017 | Regulation of solvent tolerance in Pseudomonas putidaS12 mediated by mobile elements | Microbial Biotechnology | Hosseini R., Kuepper J., Koebbing S., Blank L.M., Wierckx N. and de Winde J.h | https://doi.org/10.1111/1751-7915.12495 |
| 2017 | Dynamic regulation of metabolic flux in engineered bacteria using a pathway-independent quorum-sensing circuit | Nature Biotechnology | Gupta A., Brockman Reizman I., Reisch C. and Prather K. | https://doi.org/10.1038/nbt.3796 |
| 2017 | Cellulolytic RoboLector - towards an automated high-throughput screening platform for recombinant cellulase expression | Journal of Biological Engineering | Mühlmann M, Kunze M., Ribeiro J., Geinitz B., Lehmann C., Schwaneberg U., Commandeur U. and Büchs J. | https://doi.org/10.1186/s13036-016-0043-2 |
| 2017 | Comparative evaluation of phototrophic microtiter plate cultivation against laboratory-scale photobioreactors | Bioprocess and Biosystems Engineering | Morschett H., Schiprowski D., Rohde J., et al. | https://doi.org/10.1007/s00449-016-1731-5 |
| 2017 | The Experiment Data Depot: a web-based software tool for biological experimental data storage, sharing, and visualization | ACS Synth. Biol. | Morrell W., Birkel G., Forrer M., Lopez T., Backman T., Dussault M., Petzold C.J., et al. | https://doi.org/10.1021/acssynbio.7b00204 |
| 2017 | Beschleunigte Bioprozessentwicklung im automatisierten Mikromaßstab | Biospektrum | Holger Morschett, Stephan Noack, Marco Oldiges | https://doi.org/10.1007/s12268-017-0838-9 |
| 2016 | Zymomonas mobilis as a model system for production of biofuels and biochemicals | Microbial Biotechnology | Shihui Yang Qiang Fei Yaoping Zhang Lydia M. Contreras Sagar M. Utturkar Steven D. Brown Michael E. Himmel Min Zhang | https://doi.org/10.1111/1751-7915.12408 |
| 2016 | Quasi-continuous parallel online scattered light, fluorescence and dissolved oxygen tension measurement combined with monitoring of the oxygen transfer rate in each well of a shaken microtiter plate | Microbial Cell Factories | Ladner T., Held M., Flitsch D., Beckers M. and Büchs J. | https://doi.org/10.1186/s12934-016-0608-2 |
| 2016 | High-throughput strategies for the discovery and engineering of enzymes for biocatalysis | Bioprocess and Biosystems Engineering | Jacques P., Béchet M., Bigan M. et al. | https://doi.org/10.1007/s00449-016-1690-x |
| 2016 | High-throughput fermentation screening for the yeast Yarrowia lipolytica with real-time monitoring of biomass and lipid production | Microbial Cell Factories | Back A., Rossignol T., Krier F., Nicaud J.-M. and Dhulster P. | https://doi.org/10.1186/s12934-016-0546-z |
| 2016 | An improvement of surfactin production by B. subtilis BBG131 using design of experiments in microbioreactors and continuous process in bubbleless membrane bioreactor | Bioresource Technology | Motta Dos Santos L. F., Coutte F., Ravallec R., Dhulster P., Tournier-Couturier L., Jacques P. | https://doi.org/10.1016/j.biortech.2016.07.053 |
| 2016 | Identification of Essential Genetic Baculoviral Elements for Recombinant Protein Expression by Transactivation in Sf21 Insect Cells | PLoS ONE | Bleckmann M, Schürig M, Chen F-F, Yen Z-Z, Lindemann N, Meyer S, et al. | https://doi.org/10.1371/journal.pone.0149424 |
| 2016 | Fast plasmid based protein expression analysis in insect cells using an automated SplitGFP screen | Biotechnology and Bioengineering | Bleckmann, M., Schmelz, S., Schinkowski, C., Scrima, A. and van den Heuvel, J. | https://doi.org/10.1002/bit.25956 |
| 2015 | Improvement of glucaric acid production in E. coli via dynamic control of metabolic fluxes | Metabolic Engineering Communications | Irene M. Brockman Reizman, Andrew R. Stenger, Chris R. Reisch, Apoorv Gupta, Neal C. Connors, Kristala L.J. Prather | https://doi.org/10.1016/j.meteno.2015.09.002 |
| 2015 | Improvement of glucaric acid production in E. coli via dynamic control of metabolic fluxes | Metabolic Engineering Communications | Irene M. Brockman Reizman, Andrew R. Stenger, Chris R. Reisch, Apoorv Gupta, Neal C. Connors, Kristala L. J. Prather | https://doi.org/10.1016/j.meteno.2015.09.002 |
| 2015 | Exploring the role of sigma factor gene expression on production by Corynebacterium glutamicum: sigma factor H and FMN as example | Frontiers in Microbiology | Taniguchi H. and Wendisch V. F. | https://doi.org/10.3389/fmicb.2015.00740 |
| 2015 | A TatABC-Type Tat Translocase Is Required for Unimpaired Aerobic Growth of Corynebacterium glutamicum ATCC13032 | PLoS ONE | Oertel D., Schmitz S., Freudl R. | https://doi.org/10.1371/journal.pone.0123413 |
| 2015 | Genomic Analysis and Isolation of RNA Polymerase II Dependent Promoters from Spodoptera frugiperda | PLoS ONE | Bleckmann M., Fritz M. H.-Y., Bhuju S., Jarek M., Schürig M., Geffers R., Benes V., Besir H., van den Heuvel J. | https://doi.org/10.1371/journal.pone.0132898 |
| 2015 | Bioprocess automation on a Mini Pilot Plant enables fast quantitative microbial phenotyping | Microbial Cell Factories | Unthan S.,Radek A.,Wiechert W.,Oldiges M. and Noack S. | https://doi.org/10.1186/s12934-015-0216-6 |
| 2015 | Fed-batch like cultivation in a micro-bioreactor: screening conditions relevant for Escherichia coli based production processes | SpringerPlus | Toeroek C., Cserjan-Puschmann M., Bayer K. and Striedner G | https://doi.org/10.1186/s40064-015-1313-z |
| 2015 | Modeling leucine's metabolic pathway and knockout prediction improving the production of surfactin, a biosurfactant from Bacillus subtilis | Biotechnology Journal | Coutte F., Niehren J., Dhali D., John M., Versari C. and Jacques Ph. | https://doi.org/10.1002/biot.201400541 |
| 2015 | High‐throughput micro‐scale cultivations and chromatography modeling: Powerful tools for integrated process development | Biotechnology and Bioengineering | Baumann P., Hahn T. and Hubbuch J. | https://doi.org/10.1002/bit.25630 |
| 2015 | Parallel use of shake flask and microtiter plate online measuring devices (RAMOS and BioLector) reduces the number of experiments in laboratory-scale stirred tank bioreactors | Journal of Biological Engineering | Wewetzer S. J., Kunze M., Ladner T., Luchterhand B., Roth S., Rahmen N., Kloß R., Costa e Silva A., Regestein L. and Büchs J. | https://doi.org/10.1186/s13036-015-0005-0 |
| 2015 | Chassis organism from Corynebacterium glutamicum - a top-down approach to identify and delete irrelevant gene clusters | Biotechnol J. | Unthan S., Baumgart M., Radek A., Herbst M., Siebert D., Brühl N., Bartsch A., Bott M., Wiechert W., Marin K., Hans S., Krämer R., Seibold G., Frunzke J., Kalinowski J., Rückert C., Wendisch V.F., Noack S. | https://doi.org/10.1002/biot.201400041 |
| 2014 | Combinatorial Strategies for Improving Multiple-Stress Resistance in Industrially Relevant Escherichia coli Strains | American Society for Microbiology | Rebecca M. Lennen, Markus J. Herrgård | https://doi.org/10.1128/AEM.01542-14 |
| 2014 | Using Synthetic Biological Parts and Microbioreactors to Explore the Protein Expression Characteristics of Escherichia coli | ACS Synthetic Biology | Gorochowski T. E., van den Berg E., Kerkman R., Roubos J. A. and Bovenberg R. A. L. | https://doi.org/10.1021/sb4001245 |
| 2014 | Global analysis of protein structural changes in complex proteomes | Nature Biotechnology | Feng Y., De Franceschi G., Kahraman A., Soste M., Melnik A., Boersema P. J., Polverino de Laureto P., Nikolaev Y., Oliveira A. P. and Picotti P. | https://doi.org/10.1038/nbt.2999 |
| 2014 | Chassis organism from Corynebacterium glutamicum - a top-down approach to identify and delete irrelevant gene clusters | Biotechnology Journal | Unthan S., Baumgart M., Radek A., Herbst M., Siebert D., Brühl N., Bartsch A., Bott M., Wiechert W., Marin K., Hans S., Krämer R., Seibold G., Frunzke J., Kalinowski J., Rückert C., Wendisch V. F. and Noack S. | https://doi.org/10.1002/biot.201400041 |
| 2014 | Rapid assessment of oxygen transfer impact for Corynebacterium glutamicum | Bioprocess and Biosystems Engineering | Käß F., Prasad A., Tillack J., Moch M., Giese H., Büchs J., Wiechert W. and Oldiges M. | https://doi.org/10.1007/s00449-014-1234-1 |
| 2014 | Comprehensive clone screening and evaluation of fed-batch strategies in a microbioreactor and lab scale stirred tank bioreactor system: application on Pichia pastoris producing Rhizopus oryzae Lipase | Microbial Cell Factories | Hemmerich J., Adelantado N., Barrigón J.M., Ponte X., Hörmann A., Ferrer P., Kensy F. and Valero F. | https://doi.org/10.1186/1475-2859-13-36 |
| 2014 | SoxR as a Single-Cell Biosensor for NADPH-Consuming Enzymes in Escherichia coli | ACS Synthetic Biology | Siedler S., Schendzielorz G., Binder S., Eggeling L., Bringer S. and Bott M. | https://doi.org/10.1021/sb400110j |
| 2014 | Taking Control over Control: Use of Product Sensing in Single Cells to Remove Flux Control at Key Enzymes in Biosynthesis Pathways | ACS Synthetic Biology | Schendzielorz G., Dippong M., Grünberger A., Kohlheyer D., Yoshida A., Binder S., Nishiyama C., Nishiyama M., Bott M. and Eggeling L. | https://doi.org/10.1021/sb400059y |
| 2014 | Beyond Growth Rate 0.6: What Drives Corynebacterium glutamicum to Higher Growth Rates in Defined Medium | Biotechnology and Bioengineering | Unthan S., Grünberger A., van Ooyen J., Gätgens J., Heinrich J., Paczia N., Wiechert W., Kohlheyer D. and Noack S. | https://doi.org/10.1002/bit.25103 |
| 2014 | Application of a Genetically Encoded Biosensor for Live Cell Imaging of L-Valine Production in Pyruvate Dehydrogenase Complex-Deficient Corynebacterium glutamicum Strains | PLoS ONE | Mustafi N., Grünberger A., Mahr R., Helfrich S., Nöh K., Blombach B., Kohlheyer D. and Frunzke J. | https://doi.org/10.1371/journal.pone.0085731 |
| 2014 | Analysis of SOS-Induced Spontaneous Prophage Induction in Corynebacterium glutamicum at the Single-Cell Level | Journal of Bacteriology | Nanda A. M., Heyer A., Krämer C., Grünberger A., Kohlheyer D. and Frunzke J. | https://doi.org/10.1128/JB.01018-13 |
| 2013 | Transposon Mutagenesis Identified Chromosomal and Plasmid Genes Essential for Adaptation of the Marine Bacterium Dinoroseobacter shibae to Anaerobic Conditions | Journal of Bacteriology | Matthias Ebert, Sebastian Laaß, Melanie Burghartz, Jörn Petersen, Sebastian Koßmehl, Lars Wöhlbrand, Ralf Rabus, Christoph Wittmann, Petra Tielen, Dieter Jahna | https://doi.org/10.1128/JB.00860-13 |
| 2013 | IpsA, a novel LacI-type regulator, is required for inositol-derived lipid formation in Corynebacteria and Mycobacteria | BMC Biology | Baumgart M., Luder K., Grover S., Gätgens C., Besra G.S. and Frunzke J. | https://doi.org/10.1186/1741-7007-11-122 |
| 2013 | Complex Regulation of the Phosphoenolpyruvate Carboxykinase Gene pck and Characterization of Its GntR-Type Regulator IolR as a Repressor of myo-Inositol Utilization Genes in Corynebacterium glutamicum | Journal of Bacteriology | Klaffl S., Brocker M., Kalinowski J., Eikmanns B.J. and Bott M. | https://doi.org/10.1128/JB.00265-13 |
| 2013 | Systems metabolic engineering of Corynebacterium glutamicum for production of the chemical chaperone ectoine. | Microbial Cell Factories | Becker J., Schäfer R., Kohlstedt M., Harder B.J., Borchert N.S., Stöveken N., Bremer E. and Wittmann C. | https://doi.org/10.1186/1475-2859-12-110 |
| 2013 | Visualization of Imbalances in Sulfur Assimilation and Synthesis of Sulfur-Containing Amino Acids at the Single-Cell Level | Applied and Environmental Microbiology | Hoffmann K., Grünberger A., Lausberg F., Bott M. and Eggeling L. | https://doi.org/10.1128/AEM.01804-13 |
| 2013 | Construction of a Prophage-Free Variant of Corynebacterium glutamicum ATCC 13032 for Use as a Platform Strain for Basic Research and Industrial Biotechnology. | Applied and Environmental Microbiology | Baumgart M., Unthan S., Rückert C., Sivalingam J., Grünbergerr A., Kalinowski J., Bott M., Noack S. and Frunzke J. | https://doi.org/10.1128/AEM.01634-13 |
| 2013 | Ornithine cyclodeaminase-based proline production by Corynebacterium glutamicum | Microbial Cell Factories | Jensen J.V.K. and Wendisch V.F. | https://doi.org/10.1186/1475-2859-12-63 |
| 2013 | Growth and fermentation of D-xylose by Saccharomyces cerevisiae expressing a novel D-xylose isomerase originating from the bacterium Prevotella ruminicola TC2-24 | Biotechnology for Biofuels | Hector R.E., Dien B.S., Cotta M.A. and Mertens J.A. | https://doi.org/10.1186/1754-6834-6-84 |
| 2013 | Recombineering in Corynebacterium glutamicum combined with optical nanosensors: a general strategy for fast producer strain generation | Nucleic Acids Research | Binder S., Siedler S., Marienhagen J., Bott M. and Eggeling L. | https://doi.org/10.1093/nar/gkt312 |
| 2013 | Destabilized eYFP variants for dynamic gene expression studies in Corynebacterium glutamicum | Microbial Biotechnology | Hentschel E., Will C., Mustafi N., Burkovski A., Rehm N. and Frunzke J. | https://doi.org/10.1111/j.1751-7915.2012.00360.x |
| 2013 | Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments | Biotechnology & Bioengineering | Grünberger A., van Ooyen J., Paczia N., Rohe P., Schiendzielorz G., Eggeling L., Wiechert W., Kohlheyer D. and Noack S. | https://doi.org/10.1002/bit.24616 |
| 2012 | Fed-Batch Microbioreactor Platform for Scale Down and Analysis of a Plasmid DNA Production Process | Biotechnology and Bioengineering | Diana M. Bower, Kevin S. Lee, Rajeev J. Ram, Kristala L.J. Prather | https://doi.org/10.1002/bit.24498 |
| 2012 | Short-chain fluorescent tryptophan tags for on-line detection of functional recombinant proteins. | BMC Biotechnology | Siepert E.-M., Gartz E., Tur M.K., Delbrück H., Barth S. and Büchs J. | https://doi.org/10.1186/1472-6750-12-65 |
| 2012 | Quantification of proteome dynamics in Corynebacterium glutamicum by 15N-labeling and selected reaction monitoring | Journal of Proteomics | Voges R. and Noak S. | https://doi.org/10.1016/j.jprot.2012.03.020 |
| 2012 | Expression of recombinant staphylokinase in the methylotrophic yeast Hansenula polymorpha | BMC Biotechnology | Moussa M., Ibrahim M., El Ghazaly M., Rohde J., Gnoth S., Anton A., Kensy F. and Mueller F. | https://doi.org/10.1186/1472-6750-12-96 |
| 2012 | An automated workflow for enhancing microbial bioprocess optimization on a novel microbioreactor platform | Microbial Cell Factories | Rohe P., Venkanna D., Kleine B., Freudl R. and Oldiges M. | https://doi.org/10.1186/1475-2859-11-144 |
| 2012 | The development and application of a single-cell biosensor for the detection of L-methionine and branched-chain amino acids | Metabolic Engineering | Mustafi N., Grünberger A., Kohlheyer D., Bott M. and Frunzke J. | https://doi.org/10.1016/j.ymben.2012.02.002 |
| 2012 | A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level | Genome Biology | Binder S., Schendzielorz G., Stabler N., Krumbach K., Hoffmann K., Bott M. and Eggeling L. | https://doi.org/10.1186/gb-2012-13-5-r40 |
| 2012 | Hochparallele Bioprozessentwicklung in geschüttelten MikrobioreaktorenHigh-Throughput Bioprocess Development in Shaken Microbioreactors | Chemie Ingenieur Technik | Wenk P., Hemmerich J., Müller C. and Kensy F. | https://doi.org/10.1002/cite.201100206 |
| 2012 | Real-time determination of intracellular oxygen in bacteria using a genetically encoded FRET-based biosensor | BMC Biology | Potzkei J., Kunze M., Drepper T., Gensch T., Jaeger K.-E. and Büchs J. | https://doi.org/10.1186/1741-7007-10-28 |
| 2011 | Growth independent rhamnolipid production from glucose using the non-pathogenic Pseudomonas putida KT2440 | Microbial Cell Factories | Wittgens A., Tiso T., Arndt T.T., Wenk P., Hemmerich J., Müller C., Wichmann R., Küpper B., Zwick M., Wilhelm S., Hausmann R., Syldatk C., Rosenau F. and Blank L.M. | https://doi.org/10.1186/1475-2859-10-80 |
| 2010 | Bioprocess control in Microscale: Scalable fermentations in disposable and user-friendly microfluidic systems | Microbial Cell Factories | Funke M., Buchenauer A., Mokwa W., Kluge S., Hein L., Müller C., Kensy F. and Büchs J. | https://doi.org/10.1186/1475-2859-9-86 |
| 2010 | Microfluidic BioLector - Microfluidic Bioprocess Control in Microtiter Plates | Biotechnology & Bioengineering | Funke M., Buchenauer A., Schnakenberg U., Mokwa W., Diederichs S., Mertens A., Müller C., Kensy F. and Büchs J. | https://doi.org/10.1002/bit.22825 |
| 2010 | Flavin Mononucleotide-Based Fluorescent Reporter Proteins Outperform Green Fluorescent Protein-Like Proteins as Quantitative In Vivo Real-Time Reporters | Applied and Environmental Microbiology | Drepper T., Huber R. Heck A., Circolone F., Hillmer A.-K., Büchs J. and Jaeger K.-E. | https://doi.org/10.1128/AEM.00701-10 |
| 2010 | Replication methods and tools in high-throughput cultivation processes - recognizing potential variations of growth and product formation by on-line monitoring | BMC Biotechnology | Huber R., Palmen T.G., Ryk N., Hillmer A.-K., Luft K., Kensy F. and Büchs J. | https://doi.org/10.1186/1472-6750-10-22 |
| 2010 | High-throughput screening of Hansenula polymorpha clones in the batch compared with the controlled-release fed-batch mode on a small scale | FEMS Yeast Research | Scheidle M., Jeude M., Dittrich B., Denter S., Kensy F., Suckow M., Klee D. and Büchs J. | https://doi.org/10.1111/j.1567-1364.2009.00586.x |
| 2010 | Charakterisierung von Cellulasepräparationen mittels Streulicht | Chemie Ingenieur Technik | Wulfhorst H., Jäger G., Ellinidou E., Büchs J. and Spiess A. | https://doi.org/10.1002/cite.200900126 |
| 2009 | Scale-up from microtiter plate to laboratory fermenter: Evaluation by online monitoring techniques of growth and protein expression in Escherichia coli and Hansenula polymorpha fermentations | Microbial Cell Factories | Kensy F., Engelbrecht C. and Büchs J. | https://doi.org/10.1186/1475-2859-8-68 |
| 2009 | Asymmetric division of Hansenula polymorpha reflected by a drop of light scatter intensity measured in batch microtiter plates cultivations at phosphate limitation | Biotechnol. Bioeng. | Kottmeier K., Weber J., Müller M., Bley T. and Büchs J. | https://doi.org/10.1002/bit.22410 |
| 2009 | Validation of a high-throughput fermentation system based on online monitoring of biomass and fluorescence in continuously shaken microtiter plates | Microbial Cell Factories | Kensy F., Zang E., Faulhammer F., Tan R.-K. and Büchs J. | https://doi.org/10.1186/1475-2859-8-31 |
| 2009 | The baffled microtiter plate: Increased oxygen transfer and improved online monitoring in small scale fermentations | Biotechnology & Bioengineering | Funke M., Diederichs S., Kensy F., Müller C. and Büchs J. | https://doi.org/10.1002/bit.22341 |
| 2009 | Oxygen transfer phenomena in 48-well microtiter plates: Determination by optical monitoring of sulfite oxidation and verification by real-time measurement during microbial growth | Biotechnol. Bioeng. | Kensy F., Zimmermann H.F., Knabben I., Anderlei T., Trauthwein H., Dingerdissen U. and Büchs J. | https://doi.org/10.1002/bit.20373 |