Vi-CELL BLU vs. Vi-CELL XR: Comparison of System Specifications

Cell Viability Vi-CELL BLU with carouselBased on customer feedback, we made these enhancements for Vi-CELL BLU cell viability analyzer:

  • Compatibility with a 96-well plate
  • Carousel accommodates more sample cups
  • Faster sample processing time
  • Smaller sample volume required
  • Easier reagent loading
  • Take up less bench space with monitor incorporated in system
  • Facilitates 21 CFR Part 11 compliance

The Vi-CELL BLU automates the trypan blue dye exclusion method for cell viability and counting using advanced liquid handling and imaging technology for applications in biopharmaceutical quality control and pharmacology. With the Vi-CELL BLU you automate the entire analysis process – sample aspiration, trypan blue mixing, image analysis and instrument cleaning – to revolutionize the speed, reliability and reproducibility of results, and it provides critical information manual cell counting methods simply cannot offer.


Single sample analysis time 180 sec < 130 sec Normal Mode < 90 sec Fast Mode
Carousel loading 12 position carousel 24 position carousel
Microplate loading - Standard multi–well microplates
Cell Viability Method Trypan blue dye exclusion Trypan blue dye exclusion
Cell Size Range 2–70 μm 2–60 μm
Focus System Autofocus Autofocus
Image Transfer Firewire USB 3.0
Camera Sensor Size 1280x960 2048x2048
Captured Image Size 882x661 pixels 2048x2048
Analyzed Image Dimensions 832x611 μm 1000x1000 μm
Effective Resolution 1 μm per pixel 0.5 μm per pixel
Imaged volume per frame 43 nL 65 nL
Minimum Sample Volume 500 μL 200 μL Normal Mode 170 μL Fast Mode
Cell Density Range 5x104 – 1x107 cells/mL 5x104 – 1.5x107 cells/mL
Counting Accuracy ± 10% ± 10%
Counting repeatability ± 10% ± 5%
Reagent Pack 200 activities per pack 310 activities per pack
Facilitates 21 CFR Part 11 compliance Yes Yes
Data formats TXT, MS Excel CSV, PDF, Encrypted Binary
Touchscreen interface Depends on external PC Integrated
SQL compatible database No Yes
Single Sign-On (SSO) No Yes
Computer System External PC, Windows 7 Professional Integrated PC, Windows 10 Enterprise LTSC, 64 bit
Computer System Specifications Varies depending on configuration ordered 6th i7–6700 Generation Intel CPU 4 cores
at 3.4 GHz 16 GB DDR4–2400 RAM
Mini–ITX Motherboard 500 GB
Samsung EVO 850 SSD
Connectivity Via PC system 2 x USB 3.0 ports, Gigabit Ethernet
Height 44.5 cm (17.5 in) excluding PC 45 cm (16.5 in)
Width 38 cm (15 in) excluding PC 54 cm (21 in)
Depth 41 cm (16 in) excluding PC 42 cm (18 in)
Weight 11.3 Kg (25 lb) excluding PC 28 Kg (63 lb)
Power 41 cm (16 in) excluding PC 42 cm (18 in)
Depth Power: 50 watts (65 watts max) Voltages: 100V, 120V, 220V, or 240 V50/60 Hz Power: 50 watts (65 watts max) Voltages: 100V, 120V, 220V, or 240 V50/60 Hz

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